Can we omit anthracyclins from the neoadjuvant chemotherapy in TNBCs? Anthracyclins carry some annoying early side effects like alopecia and some serious side effects such as cardiomyopathy and second malignancies. Many patients who are not tolerating such effects are eager to avoid anthracyclins. We posed the question to Dr. Mohsen Mohtar (professor of Clinical Oncology, at Cairo University) in our live discussion, and he clearly explains the evidence to us.