A systematic review and meta-analysis of 33 studies that included 4,330 #breast_cancer patients and was done to compare effectiveness of behavioral graded activities alone or combined with psychological therapies on long term symptoms. Behavioral graded activity is a gradual increase of the daily physical activity under supervision of a physiotherapist while psychological therapies included cognitive behavioral therapy and acceptance commitment therapy.

The study that was presented In the European breast cancer conference showed that patients who underwent psychological therapies combined with behavioral graded activities demonstrated significant effects compared with those receiving neither. These included significant improvements in fatigue, anxiety, depression, psychological distress, physical activity, and quality of life