Hepatobiliary Cancer

COSMIC-312 trial

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In COSMIC-312 trial, first line #Cabozantinib plus #atezolizumab improved PFS versus #sorafenib for patients with advanced HCC. In this phase...

RTOG 1112 trial

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The addition of stereotactic body radiation therapy (SBRT) to sorafenib for patients with hepatocellular carcinoma (HCC) improved PFS and OS...

HIMALAYA trial

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The #FDA has approved Tremelimumab plus Durvalumab for patients with unresectable #Hepatocellular Carcinoma. This approval was based on the results...

FDA approval of bevacizumab biosimilar

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On September 28th 2022, the FDA has approved Celltrion’s #bevacizumab biosimilar (bevacizumab-adcd) in six types of cancers which are: metastatic...

RATIONALE-301 trial

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In the non-inferiority, RATIONALE-301 study presented by Dr. Masatoshi Kudo, Single agent Tislelizumab (TIS), an anti-PD-1 monoclonal antibody, showed comparable...

Testing the combination of immunotherapy and anti-VEGFR in HCC

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In a phase III study presented by Shukui Qin, the combination of #immunotherapy plus an anti-angiogenic TKI showed effectiveness as...

TOPAZ-1 trial

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The FDA has approved #durvalumab (Imfinzi) in combination with gemcitabine and cisplatin in adult patients with locally advanced or metastatic...

LEAP-002 trial

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In the phase III LEAP-002 study presented by Richard Finn, adding pembrolizumab to first line #Lenvatinib in HCC patients improved...