News

DESTINY-Breast02 trial: Trastuzumab deruxtecan after failure on TDM-1, An Update

Oncologyme  /  Apr 30, 2023

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In the phase 3 DESTINY-Breast02 trial, #Trastuzumab deruxtecan (T-DXd) improved the PFS and OS in patients with HER2-positive metastatic breast...

After a median follow-up of 67.6 months, the 5-year EFS rate was 70.7% in the carboplatin arm vs 64.1% in the control arm (HR, 0.798; P = 0.081). In patients younger than 50 years, the 5-year EFS rate was 74.2% vs 61.7%, respectively (HR, 0.642; P = .004).

Oncologyme  /  Apr 30, 2023

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On December 9, 2022, #FDA has approved #Atezolizumab for adult and pediatric unresectable or metastatic #alveolar soft part #sarcoma (ASPS). The...

RxPONDER PRO sub-study: Impact of chemotherapy on cognitive functions in patients with early breast cancer.

Oncologyme  /  Apr 30, 2023

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In the #RxPONDER PRO sub-study presented by Dr. Irene Kang at the 2022 San Antonio Breast Cancer Symposium (SABCS) Annual...

CheckMate 914 trial: adjuvant Immunotherapy in Renal Cell Carcinoma

Oncologyme  /  Apr 30, 2023

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In the phase 3 CheckMate 914 trial, Adjuvant #nivolumab plus #ipilimumab failed to improve the clinical outcomes in patients with...

New FDA approval for Pembrolizumab in the adjuvant treatment of NSCLC.

Oncologyme  /  Apr 30, 2023

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On January 26, 2023, the #FDA has approved #pembrolizumab for adjuvant treatment of NSCLC patients following complete resection and platinum-based...

STIC CTC trial: the use of circulating tumor cell (CTC) to guide the treatment in metastatic breast cancer.

Oncologyme  /  Apr 30, 2023

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In the phase 3 STIC CTC trial, overall survival (OS) was improved when circulating tumor cell (CTC) count was used...

PURE 01 trial: Neoadjuvant Pembrolizumab for Muscle-invasive Bladder Carcinoma

Oncologyme  /  Apr 30, 2023

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In the phase II PURE-01 trial, #neoadjuvant #pembrolizumab has shown to improve the clinical outcomes in patients with muscle-invasive #bladder...

monarchE trial: Abemaciclib in the adjuvant setting of HR-positive breast cancer

Oncologyme  /  Apr 30, 2023

In the preplanned interim analysis of #monarchE trial, the addition of #abemaciclib to adjuvant endocrine therapy improved the invasive disease-free...

In a phase III Indian study, the addition of weekly carboplatin significantly improved overall survival and event-free survival when added to a taxane-anthracycline neoadjuvant chemotherapy regimen for patients with locally advanced triple-negative breast cancer.

Oncologyme  /  Apr 30, 2023

In the phase 2, PACE trial, the combination of #palbociclib plus fulvestrant did not improve significantly PFS compared with fulvestrant...

Neoadjuvant Carboplatin Shows Improved Survival in TNBC, Indian study

Apr 16, 2023

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In a phase III Indian study, the addition of weekly carboplatin significantly improved overall survival and event-free survival when added...